To reduce expression of gene products not required under vibrating-sex-toys-and-dildos stress conditions, eukaryotic cells form large and complex cytoplasmic aggregates of RNA and proteins (stress granules; SGs), where transcripts are kept translationally inert.The overall composition of SGs, as well as their assembly requirements and regulation th
Biofilm formation is a conserved strategy for long-term bacterial survival in nature and during infections.Biofilms are multicellular aggregates of cells enmeshed in an extracellular matrix.The RetS, GacS and LadS sensors control the switch from a planktonic to a biofilm mode of growth in Pseudomonas aeruginosa.Here we detail our approach to identi
ObjectiveIdentify every paediatric surgical article published in 1998 and every paediatric surgical article published in 2013, and determine which study designs were used and whether they were appropriate for robustly assessing Toggle Switch interventions in surgical conditions.MethodsA systematic review was conducted according to a pre-specified p
Background and objectives: T regulatory lymphocytes (Treg) are one of the subsets of T-lymphocytes involved in the interaction of neoplastic tumors and the host immune system, and they may impair the immune reaction against cancer.It has been shown that Treg are increased in the peripheral blood of patients with various cancers.In colorectal cancer
Introduction Forensic studies often found high rates of major psychiatric and substance use disorders among inmates.These factors are linked to criminality in general, however, their involvement in recidivism among this population seems to be more important to determine.Objectives The aim of this study is to determinesociodemographic, psychiatric a